Assay Detail
Binding
CHEMBL3855902
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BRD4 bromodomain 1 (unknown origin) by Alphascreen assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.97 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3979343 | — | — | 1 | 5.22 |
| CHEMBL3959351 | — | — | 1 | 4.97 |
| CHEMBL3942643 | — | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3979343 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL3959351 | — | IC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL3942643 | — | IC50 | = | 18800.0 | nM | 4.73 |