Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3856483

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human CDK9 (1 to 372 residues)/cyclin T1 (1 to 726 residues) in presence of 33P-ATP by scintillation counting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

CDK9/cyclin T1 (CHEMBL2111389)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.
Sonawane YA, Taylor MA, Napoleon JV, Rana S, Contreras JI, Natarajan A.
J Med Chem (2016) 59 : 8667 -8684
PubMed 27171036 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3969723 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3969723 IC50 = 20.0 nM 7.70