Assay Detail
Binding
CHEMBL3856503
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of M-phase starfish oocytes CDK1/cyclin B after 30 mins by [gamma-33P]ATP based scintillation counting analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Asteroidea |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.07 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL270687 | MERIOLIN 5 | — | 1 | 8.15 |
| CHEMBL270897 | MERIOLIN 2 | — | 1 | 7.24 |
| CHEMBL270686 | MERIOLIN 3 | — | 1 | 6.77 |
| CHEMBL405665 | MERIOLIN 1 | — | 1 | 6.11 |
| CHEMBL270346 | MERIOLIN 9 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL270687 | MERIOLIN 5 | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL270897 | MERIOLIN 2 | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL270686 | MERIOLIN 3 | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL405665 | MERIOLIN 1 | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL270346 | MERIOLIN 9 | IC50 | > | 10000.0 | nM | - |