Assay Detail
Binding
CHEMBL3856532
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK9/cyclin T1 (unknown origin) using cdk7tide peptide as substrate
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.56 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3977324 | — | — | 1 | 9.00 |
| CHEMBL3948080 | — | — | 1 | 8.70 |
| CHEMBL3673434 | — | — | 1 | 8.52 |
| CHEMBL3961341 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3977324 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL3948080 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL3673434 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL3961341 | — | IC50 | = | 10.0 | nM | 8.00 |