Assay Detail
Functional
CHEMBL3856562
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Antiproliferative activity against human PC3 cells after 96 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel diterpenoid analogs with in-vivo antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.26 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | 4.0 | 1 | 7.30 |
| CHEMBL3905153 | — | — | 1 | 6.30 |
| CHEMBL3969545 | — | — | 1 | 6.27 |
| CHEMBL3896201 | — | — | 1 | 5.83 |
| CHEMBL3946880 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3905153 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3969545 | — | IC50 | = | 540.0 | nM | 6.27 |
| CHEMBL3896201 | — | IC50 | = | 1480.0 | nM | 5.83 |
| CHEMBL3946880 | — | IC50 | = | 2510.0 | nM | 5.60 |