Assay Detail
ADMET
CHEMBL3856567
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Antiproliferative activity against HAF cells after 96 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HAF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel diterpenoid analogs with in-vivo antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.65 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | 4.0 | 1 | 7.05 |
| CHEMBL3896201 | — | — | 1 | 5.42 |
| CHEMBL3905153 | — | — | 1 | 5.40 |
| CHEMBL3969545 | — | — | 1 | 5.34 |
| CHEMBL3946880 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61 | PODOFILOX | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL3896201 | — | IC50 | = | 3850.0 | nM | 5.42 |
| CHEMBL3905153 | — | IC50 | = | 4010.0 | nM | 5.40 |
| CHEMBL3969545 | — | IC50 | = | 4540.0 | nM | 5.34 |
| CHEMBL3946880 | — | IC50 | = | 9460.0 | nM | 5.02 |