Assay Detail
Functional
CHEMBL3856578
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of colony formation in human T47D cells after 7 days by crystal violet staining based assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel diterpenoid analogs with in-vivo antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.71 | 8.59 |
| Activity | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3969545 | — | — | 2 | 8.59 |
| CHEMBL61 | PODOFILOX | 4.0 | 2 | 8.53 |
| CHEMBL3946880 | — | — | 2 | 6.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3969545 | — | EC50 | = | 2.56 | nM | 8.59 |
| CHEMBL61 | PODOFILOX | EC50 | = | 2.97 | nM | 8.53 |
| CHEMBL3946880 | — | EC50 | = | 987.0 | nM | 6.01 |
| CHEMBL3946880 | — | Activity | - | — | - | |
| CHEMBL3969545 | — | Activity | - | — | - | |
| CHEMBL61 | PODOFILOX | Activity | - | — | - |