Assay Detail
Functional
CHEMBL3856579
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Antimigratory activity in human T47D cells assessed as inhibition of cell migration after 12 hrs by crystal violet staining based transwell migration assay
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of novel diterpenoid analogs with in-vivo antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.89 | 5.19 |
| Activity | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3969545 | — | — | 2 | 5.19 |
| CHEMBL61 | PODOFILOX | 4.0 | 2 | 5.05 |
| CHEMBL3946880 | — | — | 2 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3969545 | — | EC50 | = | 6420.0 | nM | 5.19 |
| CHEMBL61 | PODOFILOX | EC50 | = | 8980.0 | nM | 5.05 |
| CHEMBL3946880 | — | EC50 | = | 37700.0 | nM | 4.42 |
| CHEMBL3946880 | — | Activity | - | — | - | |
| CHEMBL3969545 | — | Activity | - | — | - | |
| CHEMBL61 | PODOFILOX | Activity | - | — | - |