Assay Detail
Functional
CHEMBL3856713
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Protection against H202-induced oxidative injury in rat H9c2 cells assessed as increase in cell viability after 24 hrs by neutral red staining based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | H9c2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.46 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3983900 | — | — | 1 | 4.60 |
| CHEMBL3905090 | — | — | 1 | 4.52 |
| CHEMBL3908133 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3983900 | — | EC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL3905090 | — | EC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL3908133 | — | EC50 | = | 55300.0 | nM | 4.26 |