Assay Detail
Functional
CHEMBL3857129
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Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.69 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3921224 | — | — | 1 | 5.31 |
| CHEMBL2035930 | — | — | 1 | 4.38 |
| CHEMBL3914300 | — | — | 1 | 4.37 |
| CHEMBL3961590 | — | — | 1 | - |
| CHEMBL3922321 | — | — | 1 | - |
| CHEMBL3894290 | — | — | 1 | - |
| CHEMBL3970732 | — | — | 1 | - |
| CHEMBL3932251 | — | — | 1 | - |
| CHEMBL3923304 | — | — | 1 | - |
| CHEMBL3984118 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3921224 | — | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL2035930 | — | IC50 | = | 41600.0 | nM | 4.38 |
| CHEMBL3914300 | — | IC50 | = | 42900.0 | nM | 4.37 |
| CHEMBL3961590 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3922321 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3894290 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3970732 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3932251 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3923304 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL3984118 | — | IC50 | > | 50000.0 | nM | - |