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Assay Detail

CHEMBL3859174

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability after 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SGC-7901
Confidence 1 — Organism
Curated By Autocuration

Publication

Synthesis and biological evaluation of Hederacolchiside A1 derivatives as anticancer agents.
Fang Y, Yang Z, Ouyang H, Wang R, Li J, Huang H, Jin Y, Feng Y, Yang S.
Bioorg Med Chem Lett (2016) 26 : 4576 -4579
PubMed 27592134 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.77 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL444941 HEDERACOLCHISIDE A1 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL444941 HEDERACOLCHISIDE A1 IC50 = 1700.0 nM 5.77