Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3861189

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rabbit muscle glycogen phosphorylase b using 10 mM of glucose-1-phosphate as substrate preincubated for 60 mins followed by substrate addition in presence of glycogen
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glycogen phosphorylase, muscle form (CHEMBL4696)
Type SINGLE PROTEIN
Organism Oryctolagus cuniculus

Publication

Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.
Galal SA, Khattab M, Andreadaki F, Chrysina ED, Praly JP, Ragab FAF, El Diwani HI.
Bioorg Med Chem (2016) 24 : 5423 -5430
PubMed 27624527 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.75 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3916767 1 6.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3916767 IC50 = 178.0 nM 6.75