Assay Detail
Binding
CHEMBL3862241
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Thermus thermophilus HB8 IleRS L583F mutant assessed as suppression of L-[14C]isoleucyl-tRNA(Ile) formation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Thermus thermophilus HB8 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Isoleucine--tRNA ligase (CHEMBL3879837) ↗| Type | SINGLE PROTEIN |
| Organism | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
Publication
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL719 | MUPIROCIN | 4.0 | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL719 | MUPIROCIN | Ki | = | 60.0 | nM | 7.22 |