Assay Detail
Binding
CHEMBL3862244
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant Thermus thermophilus HB8 IleRS H581N/L583F double mutant assessed as suppression of L-[14C]isoleucyl-tRNA(Ile) formation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Thermus thermophilus HB8 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Isoleucine--tRNA ligase (CHEMBL3879837) ↗| Type | SINGLE PROTEIN |
| Organism | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
Publication
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.56 | 5.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL719 | MUPIROCIN | 4.0 | 1 | 5.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL719 | MUPIROCIN | Ki | = | 2730.0 | nM | 5.56 |