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Assay Detail

CHEMBL3862297

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Escherichia coli beta-galactosidase using o-nitrophenyl beta-D-galactopyranoside after 10 to 30 mins by spectrophotometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Beta-galactosidase (CHEMBL4603)
Type SINGLE PROTEIN
Organism Escherichia coli K-12

Publication

Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.
Mena-Barragán T, García-Moreno MI, Nanba E, Higaki K, Concia AL, Clapés P, García Fernández JM, Ortiz Mellet C.
Eur J Med Chem (2016) 121 : 880 -891
PubMed 26361824 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.37 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL406973 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL406973 Ki = 4300.0 nM 5.37