Assay Detail
Functional
CHEMBL3865409
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma brucei brucei expressing BS449 after 48 hrs by ATPlite-luciferase reporter gene assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.77 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL790 | CHLORHEXIDINE | 4.0 | 1 | 6.39 |
| CHEMBL3934979 | — | — | 1 | 5.88 |
| CHEMBL3974129 | — | — | 1 | 5.68 |
| CHEMBL3907022 | — | — | 1 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL790 | CHLORHEXIDINE | EC50 | = | 410.0 | nM | 6.39 |
| CHEMBL3934979 | — | EC50 | = | 1310.0 | nM | 5.88 |
| CHEMBL3974129 | — | EC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL3907022 | — | EC50 | = | 7170.0 | nM | 5.14 |