Assay Detail
Binding
CHEMBL3865461
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Binding affinity to complement factor D (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.99 | 7.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2220483 | — | — | 1 | 7.01 |
| CHEMBL346059 | — | — | 1 | 5.54 |
| CHEMBL3901198 | — | — | 1 | 5.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2220483 | — | IC50 | = | 98.0 | nM | 7.01 |
| CHEMBL346059 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL3901198 | — | IC50 | = | 3700.0 | nM | 5.43 |