Assay Detail
Functional
CHEMBL3866465
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human KBV1 cells expressing P-glycoprotein measured after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB-V1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
3-Hydrazinoindolin-2-one derivatives: Chemical classification and investigation of their targets as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.40 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504574 | — | — | 1 | 5.48 |
| CHEMBL3938499 | — | — | 1 | 5.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504574 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL3938499 | — | IC50 | = | 4800.0 | nM | 5.32 |