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Assay Detail

CHEMBL3868159

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Non-competitive inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by Lineweaver-Burk plot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Saccharomyces cerevisiae
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Oligo-1,6-glucosidase IMA1 (CHEMBL5848)
Type SINGLE PROTEIN
Organism Saccharomyces cerevisiae S288c

Publication

Synthesis and biological evaluation of novel 2,4,5-triarylimidazole-1,2,3-triazole derivatives via click chemistry as α-glucosidase inhibitors.
Wang G, Peng Z, Wang J, Li J, Li X.
Bioorg Med Chem Lett (2016) 26 : 5719 -5723
PubMed 27810241 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.83 4.83

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3891396 1 4.83

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3891396 Ki = 14780.0 nM 4.83