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Assay Detail

CHEMBL3869476

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Induction of apoptosis in mouse Panc02 cells after 72 hrs by crystal violet staining based assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Panc02
Confidence 1 — Organism
Curated By Autocuration

Target

Panc02 (CHEMBL4483283)
Type CELL-LINE
Organism Mus musculus

Publication

Novel synthetic chalcones induce apoptosis in the A549 non-small cell lung cancer cells harboring a KRAS mutation.
Wang Y, Hedblom A, Koerner SK, Li M, Jernigan FE, Wegiel B, Sun L.
Bioorg Med Chem Lett (2016) 26 : 5703 -5706
PubMed 27810244 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 1 - -
EC50 1 6.23 6.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3919996 2 6.23

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3919996 EC50 = 590.0 nM 6.23
CHEMBL3919996 Activity - -