Assay Detail
Functional
CHEMBL3870204
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New glutathione peroxidase mimetics-Insights into antioxidant and cytotoxic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.61 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3978941 | — | — | 1 | 5.14 |
| CHEMBL3889498 | — | — | 1 | 4.86 |
| CHEMBL3908579 | — | — | 1 | 4.59 |
| CHEMBL3917529 | — | — | 1 | 4.54 |
| CHEMBL3655717 | — | — | 1 | 4.49 |
| CHEMBL3980442 | — | — | 1 | 4.05 |
| CHEMBL3984449 | — | — | 1 | - |
| CHEMBL3910336 | — | — | 1 | - |
| CHEMBL3901274 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3978941 | — | IC50 | = | 7310.0 | nM | 5.14 |
| CHEMBL3889498 | — | IC50 | = | 13770.0 | nM | 4.86 |
| CHEMBL3908579 | — | IC50 | = | 25700.0 | nM | 4.59 |
| CHEMBL3917529 | — | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL3655717 | — | IC50 | = | 32670.0 | nM | 4.49 |
| CHEMBL3980442 | — | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL3984449 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL3910336 | — | IC50 | > | 500000.0 | nM | - |
| CHEMBL3901274 | — | IC50 | = | 125000.0 | nM | - |