Assay Detail
Binding
CHEMBL3871158
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of activated protein C (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.19 | 7.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3898956 | — | — | 1 | 7.41 |
| CHEMBL3897886 | — | — | 1 | 5.92 |
| CHEMBL3978462 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3898956 | — | Ki | = | 39.0 | nM | 7.41 |
| CHEMBL3897886 | — | Ki | = | 1200.0 | nM | 5.92 |
| CHEMBL3978462 | — | Ki | = | 5700.0 | nM | 5.24 |