Assay Detail
Functional
CHEMBL3872953
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Downregulation of telomerase expression in human T47D cells after 72 hrs in presence of curcumin by SYBR green-dye based RT-PCR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | T47D |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer - A comprehensive review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431701 | SILYBIN A | 3.0 | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431701 | SILYBIN A | IC50 | = | 12000.0 | nM | 4.92 |