Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3873673

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human HCT116 cells after 48 hrs by resazurin reduction assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HCT-116
Confidence 1 — Organism
Curated By Autocuration

Publication

Nitric oxide-donating derivatives of hederacolchiside A1: Synthesis and biological evaluation in vitro and in vivo as potential anticancer agents.
Fang Y, Wang R, He M, Huang H, Wang Q, Yang Z, Li Y, Yang S, Jin Y.
Bioorg Med Chem Lett (2017) 27 : 98 -101
PubMed 27866816 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL444941 HEDERACOLCHISIDE A1 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL444941 HEDERACOLCHISIDE A1 IC50 = 2200.0 nM 5.66