Assay Detail
Binding
CHEMBL3874802
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Inhibition of rice alpha-glucosidase assessed as reduction in production of D-glucose using disaccharides as substrate incubated for 10 to 30 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryza sativa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and characterization of novel, conjugated, fluorescent DNJ derivatives for α-glucosidase recognition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.94 | 7.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3972306 | — | — | 1 | 7.38 |
| CHEMBL307429 | DUVOGLUSTAT | 2.0 | 1 | 7.30 |
| CHEMBL3901171 | — | — | 1 | 7.24 |
| CHEMBL3980365 | — | — | 1 | 7.04 |
| CHEMBL1561 | MIGLITOL | 4.0 | 1 | 7.00 |
| CHEMBL3968204 | — | — | 1 | 6.96 |
| CHEMBL3918889 | — | — | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3972306 | — | IC50 | = | 42.0 | nM | 7.38 |
| CHEMBL307429 | DUVOGLUSTAT | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3901171 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL3980365 | — | IC50 | = | 91.0 | nM | 7.04 |
| CHEMBL1561 | MIGLITOL | IC50 | = | 99.0 | nM | 7.00 |
| CHEMBL3968204 | — | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL3918889 | — | IC50 | = | 2100.0 | nM | 5.68 |