Assay Detail
Binding
CHEMBL3874804
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat small intestinal brush border membrane isomaltase assessed as reduction in production of D-glucose using disaccharides as substrate incubated for 10 to 30 mins
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and characterization of novel, conjugated, fluorescent DNJ derivatives for α-glucosidase recognition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.33 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3972306 | — | — | 1 | 5.85 |
| CHEMBL3901171 | — | — | 1 | 5.39 |
| CHEMBL3980365 | — | — | 1 | 5.34 |
| CHEMBL3918889 | — | — | 1 | 5.20 |
| CHEMBL3968204 | — | — | 1 | 4.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3972306 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL3901171 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL3980365 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL3918889 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL3968204 | — | IC50 | = | 13600.0 | nM | 4.87 |