Sucrase-isomaltase, intestinal · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt P23739. Use UniProt P23739 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23739 as the stable identity anchor, then attach disease evidence before program review.
Sucrase-isomaltase, intestinal
Review this target as Sucrase-isomaltase, intestinal, mapped to UniProt P23739. Sequence length is 1841 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Sucrase-isomaltase, intestinal as ChEMBL target CHEMBL3114, mapped to UniProt P23739. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Sucrase-isomaltase, intestinal |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | P23739 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Sucrase-isomaltase, intestinal |
| UniProt Accession | P23739 |
| Component Type | Protein |
| Sequence Length | 1841 aa |
Sucrase-isomaltase, intestinal
Review this target as Sucrase-isomaltase, intestinal, mapped to UniProt P23739. Sequence length is 1841 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL432221 | 9.82 | Ki | 0.15 | Preclinical |
| CHEMBL120226 | 8.52 | Ki | 3.0 | Preclinical |
| CHEMBL184028 | 8.46 | IC50 | 3.5 | Preclinical |
| CHEMBL268675 | 8.36 | IC50 | 4.4 | Preclinical |
| CHEMBL402196 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL121283 | 8.1 | Ki | 8.0 | Preclinical |
| CHEMBL403239 | 8.07 | IC50 | 8.5 | Preclinical |
| CHEMBL120395 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL120489 | 7.8 | Ki | 16.0 | Preclinical |
| CHEMBL415713 | 7.8 | Ki | 16.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 114 | 227 | 5.8 |
| assay format | 11 | 37 | 5.5 |
| cell membrane format | 6 | 24 | 5.8 |
| tissue-based format | 3 | 14 | 5.2 |
| cell-based format | 2 | 1 | — |