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Assay Detail

CHEMBL3879954

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse P388 cells assessed as decrease in cell viability after 72 hrs by ATP-lite assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type P388
Confidence 1 — Organism
Curated By Autocuration

Publication

Compounds and therapeutical use thereof
(2005)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 8.57 8.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL444724 1 8.96
CHEMBL159 VINBLASTINE 4.0 1 8.59
CHEMBL92 DOCETAXEL ANHYDROUS 4.0 1 8.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL444724 IC50 = 1.1 nM 8.96
CHEMBL159 VINBLASTINE IC50 = 2.6 nM 8.59
CHEMBL92 DOCETAXEL ANHYDROUS IC50 = 7.0 nM 8.15