Assay Detail

CHEMBL3880917

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Potentiation of SN-38 induced cytotoxicity against human PANC1 cells assessed as SN-38 IC50 level at 1 uM after 96 hrs by CellTiter-Glo luminescence assay (Rvb = SN-38 IC50 alone = 82.5 nM)

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

PANC-1 (CHEMBL614139) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

PANC-1 (CHEMBL614139) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target PANC-1

CHEMBL614139

Anchored from Assay target.

Protein identity PANC-1

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	PANC-1
Confidence	1 — Organism
Curated By	Autocuration

Target

PANC-1 (CHEMBL614139) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Multikinase inhibitors for use in the treatment of cancer

(2009)

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.79	7.79

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1097700	—	—	1	7.79
CHEMBL1097999	E-6201	2.0	1	7.79

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1097700	—	IC50	=	16.2	nM	7.79
CHEMBL1097999	E-6201	IC50	=	16.2	nM	7.79