Assay Detail
Functional
CHEMBL3880933
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Antiproliferative activity against human DU145 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isoform Selective HDAC Inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.50 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3926370 | — | — | 1 | 6.75 |
| CHEMBL511212 | — | — | 1 | 6.72 |
| CHEMBL387924 | — | — | 1 | 6.50 |
| CHEMBL468935 | — | — | 1 | 6.50 |
| CHEMBL3943242 | — | — | 1 | 6.28 |
| CHEMBL512644 | — | — | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3926370 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL511212 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL387924 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL468935 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL3943242 | — | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL512644 | — | IC50 | = | 580.0 | nM | 6.24 |