Assay Detail
Functional
CHEMBL3880934
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Antiproliferative activity against human MCF7/ADR cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI/ADR-RES |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Isoform Selective HDAC Inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.78 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL512644 | — | — | 1 | 6.46 |
| CHEMBL511212 | — | — | 1 | 6.40 |
| CHEMBL387924 | — | — | 1 | 5.52 |
| CHEMBL468935 | — | — | 1 | 5.52 |
| CHEMBL3926370 | — | — | 1 | 5.00 |
| CHEMBL3943242 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL512644 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL511212 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL387924 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL468935 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3926370 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL3943242 | — | IC50 | - | — | - |