Assay Detail
Binding
CHEMBL3881456
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human NHE1 expressed in CHO-K1 cells assessed as inhibition of Na+/Ca+ exchange activity measured after 5 mins by BACEF-AM dye based fluorescence analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
NHE3-binding compounds and methods for inhibiting phosphate transport
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.05 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51879 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51879 | — | IC50 | = | 9.0 | nM | 8.05 |