Assay Detail
Functional
CHEMBL3881981
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human CFPAC cells assessed as growth inhibition by measuring ATP levels after 72 hrs by ATPlite assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CFPAC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multi-functional small molecules as anti-proliferative agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.29 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL598797 | CUDC-101 | 1.0 | 1 | 7.00 |
| CHEMBL604094 | — | — | 1 | 7.00 |
| CHEMBL597773 | — | — | 1 | 6.00 |
| CHEMBL3970892 | — | — | 1 | 6.00 |
| CHEMBL3907094 | — | — | 1 | 6.00 |
| CHEMBL605976 | — | — | 1 | 6.00 |
| CHEMBL596761 | — | — | 1 | 6.00 |
| CHEMBL3943805 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL598797 | CUDC-101 | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL604094 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL597773 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3970892 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3907094 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL605976 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL596761 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3943805 | — | IC50 | >= | 10000.0 | nM | - |