Assay Detail
Functional
CHEMBL3881983
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Cytotoxicity against human MIAPaCa2 cells assessed as growth inhibition by measuring ATP levels after 72 hrs by ATPlite assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MIA PaCa-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Multi-functional small molecules as anti-proliferative agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.38 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL598797 | CUDC-101 | 1.0 | 1 | 7.00 |
| CHEMBL604094 | — | — | 1 | 7.00 |
| CHEMBL3907094 | — | — | 1 | 7.00 |
| CHEMBL597773 | — | — | 1 | 6.00 |
| CHEMBL3943805 | — | — | 1 | 6.00 |
| CHEMBL3970892 | — | — | 1 | 6.00 |
| CHEMBL605976 | — | — | 1 | 6.00 |
| CHEMBL596761 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL598797 | CUDC-101 | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL604094 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3907094 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL597773 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3943805 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3970892 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL605976 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL596761 | — | IC50 | = | 1000.0 | nM | 6.00 |