Assay Detail
Functional
CHEMBL3883097
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human recombinant EP1 receptor expressed in HEK293 cells assessed as effect on calcium accumulation by Fluo-4 AM dye based FLIPR assay
95
Total Activities
95
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Prostaglandin E2 receptor EP1 subtype (CHEMBL1811) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Therapeutic compounds
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 95 | 5.85 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3976116 | — | — | 1 | 6.66 |
| CHEMBL3908432 | — | — | 1 | 5.73 |
| CHEMBL3947001 | — | — | 1 | 5.16 |
| CHEMBL3959653 | — | — | 1 | - |
| CHEMBL3959926 | — | — | 1 | - |
| CHEMBL3936540 | — | — | 1 | - |
| CHEMBL3973347 | — | — | 1 | - |
| CHEMBL3929446 | — | — | 1 | - |
| CHEMBL3948932 | — | — | 1 | - |
| CHEMBL3939358 | — | — | 1 | - |
| CHEMBL3978583 | — | — | 1 | - |
| CHEMBL3985882 | — | — | 1 | - |
| CHEMBL3939669 | — | — | 1 | - |
| CHEMBL3960007 | — | — | 1 | - |
| CHEMBL3962691 | — | — | 1 | - |
| CHEMBL3915426 | — | — | 1 | - |
| CHEMBL3925244 | — | — | 1 | - |
| CHEMBL3968751 | — | — | 1 | - |
| CHEMBL3977724 | — | — | 1 | - |
| CHEMBL3953162 | — | — | 1 | - |
| CHEMBL3919393 | — | — | 1 | - |
| CHEMBL3922121 | — | — | 1 | - |
| CHEMBL3905606 | — | — | 1 | - |
| CHEMBL3897181 | — | — | 1 | - |
| CHEMBL3920560 | — | — | 1 | - |
| CHEMBL3983069 | — | — | 1 | - |
| CHEMBL3901088 | — | — | 1 | - |
| CHEMBL3924987 | — | — | 1 | - |
| CHEMBL3975238 | — | — | 1 | - |
| CHEMBL3973312 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3976116 | — | EC50 | = | 221.0 | nM | 6.66 |
| CHEMBL3908432 | — | EC50 | = | 1873.0 | nM | 5.73 |
| CHEMBL3947001 | — | EC50 | = | 6952.0 | nM | 5.16 |
| CHEMBL3936540 | — | EC50 | - | — | - | |
| CHEMBL3951834 | — | EC50 | - | — | - | |
| CHEMBL3959926 | — | EC50 | - | — | - | |
| CHEMBL3959653 | — | EC50 | - | — | - | |
| CHEMBL1722929 | — | EC50 | - | — | - | |
| CHEMBL3922151 | — | EC50 | - | — | - | |
| CHEMBL3920796 | — | EC50 | - | — | - | |
| CHEMBL3918084 | — | EC50 | - | — | - | |
| CHEMBL3906402 | — | EC50 | - | — | - | |
| CHEMBL3905811 | — | EC50 | - | — | - | |
| CHEMBL3928130 | — | EC50 | - | — | - | |
| CHEMBL3909111 | — | EC50 | - | — | - | |
| CHEMBL3908484 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL3891401 | — | EC50 | - | — | - | |
| CHEMBL3901873 | — | EC50 | - | — | - | |
| CHEMBL3892847 | — | EC50 | - | — | - | |
| CHEMBL3921784 | — | EC50 | - | — | - | |
| CHEMBL3920756 | — | EC50 | - | — | - | |
| CHEMBL3971632 | — | EC50 | - | — | - | |
| CHEMBL3959769 | — | EC50 | - | — | - | |
| CHEMBL3918349 | — | EC50 | - | — | - | |
| CHEMBL3907809 | — | EC50 | - | — | - | |
| CHEMBL3953564 | — | EC50 | - | — | - | |
| CHEMBL3977724 | — | EC50 | - | — | - | |
| CHEMBL3973312 | — | EC50 | - | — | - | |
| CHEMBL3975238 | — | EC50 | - | — | - | |
| CHEMBL3924987 | — | EC50 | - | — | - | |
| CHEMBL3901088 | — | EC50 | - | — | - | |
| CHEMBL3983069 | — | EC50 | - | — | - | |
| CHEMBL3920560 | — | EC50 | - | — | - | |
| CHEMBL3897181 | — | EC50 | - | — | - | |
| CHEMBL3905606 | — | EC50 | - | — | - | |
| CHEMBL3922121 | — | EC50 | - | — | - | |
| CHEMBL3919393 | — | EC50 | - | — | - | |
| CHEMBL3953162 | — | EC50 | - | — | - | |
| CHEMBL3973347 | — | EC50 | - | — | - | |
| CHEMBL3968751 | — | EC50 | - | — | - | |
| CHEMBL3925244 | — | EC50 | - | — | - | |
| CHEMBL3915426 | — | EC50 | - | — | - | |
| CHEMBL3962691 | — | EC50 | - | — | - | |
| CHEMBL3960007 | — | EC50 | - | — | - | |
| CHEMBL3939669 | — | EC50 | - | — | - | |
| CHEMBL3985882 | — | EC50 | - | — | - | |
| CHEMBL3978583 | — | EC50 | - | — | - | |
| CHEMBL3939358 | — | EC50 | - | — | - | |
| CHEMBL3948932 | — | EC50 | - | — | - | |
| CHEMBL3929446 | — | EC50 | > | 10000.0 | nM | - |