Assay Detail
Binding
CHEMBL3992001
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cKIT D816H mutant (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Mast/stem cell growth factor receptor Kit (CHEMBL1936) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Pharmaceutical formulations comprising salts of a protein kinase inhibitor and methods of using same
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2105685 | AMUVATINIB HYDROCHLORIDE | -1.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2105685 | AMUVATINIB HYDROCHLORIDE | IC50 | = | 10.0 | nM | 8.00 |