Assay Detail
Binding
CHEMBL3992287
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Binding affinity to recombinant truncated N-terminal hexahistidine-tagged c-Myc (363 to 381 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS) by fluorescence polarization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Linked Myc-max small molecule inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.55 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4098292 | — | — | 1 | 9.10 |
| CHEMBL4071241 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4098292 | — | Kd | = | 0.8 | nM | 9.10 |
| CHEMBL4071241 | — | Kd | = | 10.0 | nM | 8.00 |