Use UniProt P01106 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1250348 Target Snapshot
Myc proto-oncogene protein · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P01106. Use UniProt P01106 as the stable identity anchor, then attach disease evidence before program review.
Myc proto-oncogene protein
Review this target as Myc proto-oncogene protein, mapped to UniProt P01106. Sequence length is 454 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Myc proto-oncogene protein as ChEMBL target CHEMBL1250348, mapped to UniProt P01106. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Myc proto-oncogene protein is the right protein anchor across sources, using UniProt P01106 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Myc proto-oncogene protein |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P01106 |
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UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Myc proto-oncogene protein |
| UniProt Accession | P01106 |
| Component Type | Protein |
| Sequence Length | 454 aa |
Myc proto-oncogene protein
How to read this target
Review this target as Myc proto-oncogene protein, mapped to UniProt P01106. Sequence length is 454 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5089688 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL4100737 | 9.22 | Kd | 0.6 | Preclinical |
| CHEMBL5084636 | 9.22 | IC50 | 0.6 | Preclinical |
| CHEMBL4297458 | 9.15 | IC50 | 0.7 | Clinical |
| CHEMBL5075294 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4098292 | 9.1 | Kd | 0.8 | Preclinical |
| CHEMBL5086429 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL5091333 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5084198 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL4105521 | 8.77 | Kd | 1.7 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 103 assays, 353 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 63 | 108 | 5.4 |
| assay format | 22 | 29 | 7.0 |
| single protein format | 15 | 216 | 5.6 |
| subcellular format | 3 | 0 | — |