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Assay Detail

CHEMBL3995570

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as ABTS radical scavenging activity incubated for 10 mins under dark condition
25
Total Activities
25
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Synthesis and biological evaluation of deferiprone-resveratrol hybrids as antioxidants, Aβ1-42 aggregation inhibitors and metal-chelating agents for Alzheimer's disease.
Xu P, Zhang M, Sheng R, Ma Y.
Eur J Med Chem (2017) 127 : 174 -186
PubMed 28061347 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 25 5.47 6.12

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL165 RESVERATROL 3.0 1 6.12
CHEMBL4103241 1 6.06
CHEMBL4097928 1 5.92
CHEMBL4077009 1 5.88
CHEMBL4068105 1 5.86
CHEMBL4074006 1 5.76
CHEMBL4078980 1 5.74
CHEMBL4072235 1 5.68
CHEMBL4095488 1 5.66
CHEMBL4091301 1 5.60
CHEMBL4092433 1 5.47
CHEMBL4094556 1 5.43
CHEMBL153 TROLOX 1 5.41
CHEMBL4097746 1 5.40
CHEMBL4077321 1 5.39
CHEMBL4086825 1 5.38
CHEMBL4069543 1 5.32
CHEMBL4075646 1 5.24
CHEMBL4059796 1 5.20
CHEMBL4070599 1 5.17
CHEMBL4074429 1 5.09
CHEMBL4065395 1 4.94
CHEMBL4099194 1 4.94
CHEMBL4095654 1 4.72
CHEMBL140 CURCUMIN 3.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL165 RESVERATROL IC50 = 760.0 nM 6.12
CHEMBL4103241 IC50 = 880.0 nM 6.06
CHEMBL4097928 IC50 = 1190.0 nM 5.92
CHEMBL4077009 IC50 = 1310.0 nM 5.88
CHEMBL4068105 IC50 = 1370.0 nM 5.86
CHEMBL4074006 IC50 = 1730.0 nM 5.76
CHEMBL4078980 IC50 = 1830.0 nM 5.74
CHEMBL4072235 IC50 = 2110.0 nM 5.68
CHEMBL4095488 IC50 = 2210.0 nM 5.66
CHEMBL4091301 IC50 = 2520.0 nM 5.60
CHEMBL4092433 IC50 = 3410.0 nM 5.47
CHEMBL4094556 IC50 = 3740.0 nM 5.43
CHEMBL153 TROLOX IC50 = 3890.0 nM 5.41
CHEMBL4097746 IC50 = 4020.0 nM 5.40
CHEMBL4077321 IC50 = 4030.0 nM 5.39
CHEMBL4086825 IC50 = 4170.0 nM 5.38
CHEMBL4069543 IC50 = 4790.0 nM 5.32
CHEMBL4075646 IC50 = 5720.0 nM 5.24
CHEMBL4059796 IC50 = 6290.0 nM 5.20
CHEMBL4070599 IC50 = 6740.0 nM 5.17
CHEMBL4074429 IC50 = 8120.0 nM 5.09
CHEMBL4065395 IC50 = 11400.0 nM 4.94
CHEMBL4099194 IC50 = 11500.0 nM 4.94
CHEMBL4095654 IC50 = 19200.0 nM 4.72
CHEMBL140 CURCUMIN IC50 - -