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Assay Detail

CHEMBL3997010

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of LPS-stimulated ROS production in mouse RAW264.7 cells after 22 hrs by C-400 fluorescent dye-based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type RAW264.7
Confidence 1 — Organism
Curated By Autocuration

Target

RAW264.7 (CHEMBL612557)
Type CELL-LINE
Organism Mus musculus

Publication

Inhibition of LPS-stimulated ROS production by fluorinated and hydroxylated chalcones in RAW 264.7 macrophages with structure-activity relationship study.
Bist G, Pun NT, Magar TB, Shrestha A, Oh HJ, Khakurel A, Park PH, Lee ES.
Bioorg Med Chem Lett (2017) 27 : 1205 -1209
PubMed 28159411 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.05 5.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL592005 MALVIDIN CHLORIDE 1 5.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL592005 MALVIDIN CHLORIDE IC50 = 9000.0 nM 5.05