Assay Detail
ADMET
CHEMBL3998847
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Inhibition of human ALK2 using casein as substrate in presence of 10 uM ATP by radiometric kinase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.58 | 8.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL513147 | — | — | 1 | 8.49 |
| CHEMBL4099337 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL513147 | — | IC50 | = | 3.26 | nM | 8.49 |
| CHEMBL4099337 | — | IC50 | = | 217.0 | nM | 6.66 |