Assay Detail
Binding
CHEMBL3999967
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Displacement of [3H]DPN from zebrafish delta 1b opioid receptor expressed in HEK293 cell membranes after 4 hrs by scintillation counting method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Danio rerio |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 6.49 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL13786 | — | — | 1 | 7.35 |
| CHEMBL4065055 | — | — | 1 | 6.80 |
| CHEMBL8234 | ENKEPHALIN | — | 1 | 6.76 |
| CHEMBL4095111 | — | — | 1 | 6.59 |
| CHEMBL4102609 | — | — | 1 | 6.29 |
| CHEMBL4083712 | — | — | 1 | 6.28 |
| CHEMBL4064725 | — | — | 1 | 6.27 |
| CHEMBL4101712 | — | — | 1 | 6.25 |
| CHEMBL70 | MORPHINE | 4.0 | 1 | 5.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL13786 | — | Ki | = | 45.0 | nM | 7.35 |
| CHEMBL4065055 | — | Ki | = | 158.9 | nM | 6.80 |
| CHEMBL8234 | ENKEPHALIN | Ki | = | 175.0 | nM | 6.76 |
| CHEMBL4095111 | — | Ki | = | 256.4 | nM | 6.59 |
| CHEMBL4102609 | — | Ki | = | 518.5 | nM | 6.29 |
| CHEMBL4083712 | — | Ki | = | 528.3 | nM | 6.28 |
| CHEMBL4064725 | — | Ki | = | 536.2 | nM | 6.27 |
| CHEMBL4101712 | — | Ki | = | 559.4 | nM | 6.25 |
| CHEMBL70 | MORPHINE | Ki | = | 1427.0 | nM | 5.85 |