Assay Detail
Functional
CHEMBL4000328
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Herpes simplex virus 2 G infected in human HEL cells assessed as inhibition of virus-induced cytopathic effect by visual scoring analysis
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, antiplasmodial activity and mechanistic studies of pyrimidine-5-carbonitrile and quinoline hybrids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 14 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 7.00 |
| CHEMBL4066702 | — | — | 1 | - |
| CHEMBL4088000 | — | — | 1 | - |
| CHEMBL4069858 | — | — | 1 | - |
| CHEMBL4097050 | — | — | 1 | - |
| CHEMBL4080544 | — | — | 1 | - |
| CHEMBL4104770 | — | — | 1 | - |
| CHEMBL4088409 | — | — | 1 | - |
| CHEMBL4067148 | — | — | 1 | - |
| CHEMBL4096132 | — | — | 1 | - |
| CHEMBL4078078 | — | — | 1 | - |
| CHEMBL4083981 | — | — | 1 | - |
| CHEMBL4062263 | — | — | 1 | - |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4066702 | — | EC50 | > | 4000.0 | nM | - |
| CHEMBL4088000 | — | EC50 | > | 800.0 | nM | - |
| CHEMBL4069858 | — | EC50 | > | 800.0 | nM | - |
| CHEMBL4097050 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4080544 | — | EC50 | > | 4000.0 | nM | - |
| CHEMBL4104770 | — | EC50 | > | 800.0 | nM | - |
| CHEMBL4088409 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4067148 | — | EC50 | > | 800.0 | nM | - |
| CHEMBL4096132 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4078078 | — | EC50 | > | 800.0 | nM | - |
| CHEMBL4083981 | — | EC50 | > | 4000.0 | nM | - |
| CHEMBL4062263 | — | EC50 | > | 4000.0 | nM | - |
| CHEMBL76 | CHLOROQUINE | EC50 | > | 20000.0 | nM | - |