Assay Detail
ADMET
CHEMBL4000421
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Cytotoxicity against mouse L929 cells after 5 days by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | L929 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Pyristriatins A and B: Pyridino-Cyathane Antibiotics from the Basidiomycete Cyathus cf. striatus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.01 | 8.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL329993 | EPOTHILONE A | — | 1 | 8.42 |
| CHEMBL4071721 | — | — | 1 | 4.81 |
| CHEMBL4082991 | — | — | 1 | 4.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL329993 | EPOTHILONE A | IC50 | = | 3.8 | nM | 8.42 |
| CHEMBL4071721 | — | IC50 | = | 15400.0 | nM | 4.81 |
| CHEMBL4082991 | — | IC50 | = | 16300.0 | nM | 4.79 |