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Assay Detail

CHEMBL4001448

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of LPS-induced NO production in mouse RAW264.7 cells pretreated for 30 mins followed by LPS challenge measured after 12 hrs by Griess assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type RAW264.7
Confidence 1 — Organism
Curated By Autocuration

Target

RAW264.7 (CHEMBL612557)
Type CELL-LINE
Organism Mus musculus

Publication

Triterpene saponins and megastigmane glucosides from Camellia bugiamapensis.
Huong NT, Vien LT, Hanh TT, Dang NH, Thanh NV, Cuong NX, Nam NH, Truong LH, Ban NK, Kiem PV, Minh CV.
Bioorg Med Chem Lett (2017) 27 : 557 -561
PubMed 28011215 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.66 5.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL378104 CARDAMOMIN 1 5.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL378104 CARDAMOMIN IC50 = 2200.0 nM 5.66