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Assay Detail

CHEMBL4003329

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Ellman's method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cholinesterase (CHEMBL1914)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Amino derivatives of platanic acid act as selective and potent inhibitors of butyrylcholinesterase.
Heller L, Kahnt M, Loesche A, Grabandt P, Schwarz S, Brandt W, Csuk R.
Eur J Med Chem (2017) 126 : 652 -668
PubMed 27936444 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.88 9.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4089082 1 9.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4089082 Ki = 0.131 nM 9.88