Assay Detail
Functional
CHEMBL4006650
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 at 70 hrs post dose by resazurin-based assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trypanosoma brucei brucei |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and trypanocidal activity of a library of 4-substituted 2-(1H-pyrrolo[3,2-c]pyridin-2-yl)propan-2-ols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.16 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4091859 | — | — | 1 | 6.16 |
| CHEMBL270544 | GW396574X | — | 1 | 6.16 |
| CHEMBL1090508 | — | — | 1 | 6.16 |
| CHEMBL4102086 | — | — | 1 | 6.16 |
| CHEMBL4061307 | — | — | 1 | 6.16 |
| CHEMBL4083170 | — | — | 1 | 6.16 |
| CHEMBL587208 | — | — | 1 | 6.16 |
| CHEMBL404488 | — | — | 1 | 6.16 |
| CHEMBL4103015 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4091859 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL270544 | GW396574X | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL1090508 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL4102086 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL4061307 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL4083170 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL587208 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL404488 | — | EC50 | = | 691.83 | nM | 6.16 |
| CHEMBL4103015 | — | EC50 | = | 691.83 | nM | 6.16 |