Assay Detail
Binding
CHEMBL4010459
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Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by spectrophotometric method
7
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Chemical and bioactivity of flavanones obtained from roots of Dalea pazensis Rusby.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.08 | 5.63 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL516671 | — | — | 1 | 5.63 |
| CHEMBL287556 | KOJIC ACID | — | 2 | 5.31 |
| CHEMBL4101226 | — | — | 2 | 4.30 |
| CHEMBL4063130 | — | — | 1 | - |
| CHEMBL4083227 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL516671 | — | IC50 | = | 2320.0 | nM | 5.63 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 4930.0 | nM | 5.31 |
| CHEMBL4101226 | — | IC50 | = | 49800.0 | nM | 4.30 |
| CHEMBL4063130 | — | IC50 | - | — | - | |
| CHEMBL4083227 | — | IC50 | - | — | - | |
| CHEMBL4101226 | — | Inhibition | - | % | - | |
| CHEMBL287556 | KOJIC ACID | Inhibition | - | % | - |