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Assay Detail

CHEMBL4011323

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of 15-LOX (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Polyunsaturated fatty acid lipoxygenase ALOX15 (CHEMBL2903)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Easy and rapid preparation of benzoylhydrazides and their diazene derivatives as inhibitors of 15-lipoxygenase.
Tirapegui C, Acevedo-Fuentes W, Dahech P, Torrent C, Barrias P, Rojas-Poblete M, Mascayano C.
Bioorg Med Chem Lett (2017) 27 : 1649 -1653
PubMed 28318946 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL395428 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL395428 IC50 = 1000.0 nM 6.00