Assay Detail
Functional
CHEMBL4011479
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against full length gluc-tagged Chikungunya virus 2013 Caribbean CNR20235 infected in HEK293T cells assessed as reduction in virus infection after 24 hrs by gaussia luciferase reporter gene assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structural Optimizations of Thieno[3,2-b]pyrrole Derivatives for the Development of Metabolically Stable Inhibitors of Chikungunya Virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.69 | 5.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 5.71 |
| CHEMBL3739973 | — | — | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 1970.0 | nM | 5.71 |
| CHEMBL3739973 | — | EC50 | = | 2180.0 | nM | 5.66 |